A RARE CASE OF GIANT UNRUPTURED SINUS OF VALSALVA ANEURYSM

A Rare Case of Giant Unruptured Sinus of Valsalva Aneurysm

Sinus of Valsalva aneurysm is a rare congenital disorder that usually presents with rupture of the aneurysm into adjacent cardiac structures.It usually arises from the right sinus of Valsalva which ruptures into the right ventricle or right atrium (RA).Aneurysms may also arise from the noncoronary cusp that rupture into RA.Rarely, an unruptured ane

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Early diagnosis of airway closure from pigtail signature capnogram and its management in intubated small infants undergoing general anaesthesia for surgery

Spontaneous glottis closure during expiration in infants is laguna 3hp dust collector a normal protective reflex that helps prevent alveolar and small airway collapse (due to compliant chest wall) and thereby maintains functional residual capacity.Endotracheal intubation eliminates this protective mechanism and puts the infant into the risk of hypo

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Verbal Means of Negative Assessment in Online Restaurant Reviews

The article describes the verbal means of expressing a negative assessment in online reviews.The study included online reviews on the Shashlykoff restaurant in the Russian digital directory 2GIS.The author addressed the issue of virtual genres, e.g., online reviews, online comments, etc.Online reviews as a genre appeared to be secondary and dialogi

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ELOTUZUMAB FOR THE TREATMENT OF RELAPSED OR REFRACTORY MULTIPLE MYELOMA, WITH SPECIAL REFERENCE TO ITS MODES OF ACTION AND SLAMF7 SIGNALING

Elotuzumab, targeting signaling lymphocytic activation molecule family 7 (SLAMF7), has been approved in combination with lenalidomide and dexamethasone (ELd) for relapsed/refractory multiple myeloma (MM) based on the findings of the phase III randomized trial ELOQUENT-2 (NCT01239797).Four-year follow-up analyses of ELOQUENT-2 have demonstrated that

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